Assessment of ventricular dyssynchrony: global or regional function?

Global and Regional Left Ventricular Function

Learning Objectives At the conclusion of this lecture, the participant should be able to: 1. Identify normal and abnormal left ventricular systolic function 2. Perform qualitative and quantitative assessment of left ventricular systolic function 3. Recognize the LV segments and their corresponding coronary distribution 4. Assess regional wall motion in these segments and differentiate between i...

Quantifying the role of regional dyssynchrony on global left ventricular performance.

OBJECTIVES We hypothesize that left ventricular (LV) segmental dyssynchrony, quantified by paradoxical systolic wall thinning, determines changes in global LV performance in a model of canine right ventricular (RV) pacing-induced dyssynchrony and the response to cardiac resynchronization therapy (CRT). BACKGROUND Quantification of LV dyssynchrony is important to assess the impact of CRT. ME...

Quantitative assessment of global and regional left ventricular function with low-contrast dose digital subtraction ventriculography.

Few studies have compared the use of low-contrast dose digital subtraction ventriculography with conventional ventriculography for quantitative assessment of both global and regional left ventricular function. Accordingly, 34 patients underwent conventional ventriculography using 36 ml of ionic contrast material and digital ventriculography (mask-mode) using 10 ml of contrast diluted in 10 ml o...

Reproducibility in echocardiographic assessment of the left ventricular global and regional function, the HUNT study.

AIMS The study aimed to compare the inter-observer reproducibility of new and traditional measurements of the left ventricular (LV) global and regional function. METHODS AND RESULTS Two experienced echocardiographers performed 20 complete echo/Doppler examinations and 50 analyses on ten healthy subjects. All recordings were analysed for systolic and diastolic conventional and deformation meas...

Ventricular Dilation and Electrical Dyssynchrony Synergistically Increase Regional Mechanical Nonuniformity But Not Mechanical Dyssynchrony